Immunopathology and ultrastructure of lichen planus.
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Immunopathology and ultrastructure of lichen planus.

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Published .
Written in English

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Thesis (Ph.D.) - University of Sheffield, Dept. of Dermatology, 1985.

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Open LibraryOL13959880M

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Volume 28 Ultrastructure of oral lichen planus Number 3 This study did not substantiate any theory of etiology of oral lichen planus. It seems likely that there is a relationship between the destruction of the basement membrane and the presence of inflammatory cells and fluid in intercellular spaces, but no causative agents could be by: Lichen Planus Pemphigoides. LPP is characterized by bullae arising on lichen planus papules. Some authors suggest LPP is the concurrence of lichen planus (LP) and BP, while others consider LPP as an entity in its own right. In contrast to BP, LPP is seen in younger patients and the blisters are often distributed on the distal extremities. The labeling index of the infiltrate of oral lichen planus lesions was significantly greater than that of normal mucosa, and its labeling activity redistributed, as determined by in vitro autoradiography. An electron microscopic examination of the infiltrate of lichen planus lesions of oral mucosa and skin supported the concept that the lichen planus infiltrate represents a cell mediated Cited by:   Bullous lichen planus: vesicle or bullae in conventional lichen planus (Clin Exp Dermatol ;) Lichen planus pemphigoides: bulla with mild perivascular lymphocytic infiltrate, may show neutrophils (J Am Acad Dermatol ;) Oral lichen planus: occasional parakeratosis, less acanthosis than in the skin, plasma cells in infiltrate.

  Lichen planus is a somewhat uncommon autoimmune disease that causes red, flat, and itchy bumps on the skin, nails, or irritated areas in the mouth. It can also cause hair loss. It is not a contagious disease but its exact cause is unknown, so no complete cure is possible. However, treatment may help relieving discomfort, and once the symptoms Views: 11K. NANCY W. BURKHART, BSDH, EdD, is an adjunct associate professor in the department of periodontics-stomatology at the Texas A&M College of Dentistry in Dallas. Dr. Burkhart is founder and cohost of the International Oral Lichen Planus Support Group ( and coauthor of General and Oral Pathology for the Dental Hygienist, which is in its third edition.   Lichen planus (LP) is an inflammatory autoimmune condition affecting mucous membranes and the skin. The condition affects around one per cent of all women, with it being more common in the mouth (gingival lichen planus).   Lichen planus is an inflammatory condition that affects the skin and mucous membranes. It can result in an itchy, non-infectious rash and can affect many parts of the body, including your trunk, arms, legs, scalp, nails, genitals, and mouth – when it affects the mouth, it is known as oral lichen planus.

Keywords: Basal cells, lichen planus, ultrastructure INTRODUCTION. Lichen planus is a common mucocutaneous disease affecting the skin and areas in the oral cavity. This lesion was first described by Wilson in and he compared the skin lesions of lichen planus to . Lichen planus (LP) is a rare, chronic, inflammatory autoimmune skin and mucous membrane disease. LP most commonly presents as itchy, shiny, reddish-purple spots (lesions) on the skin (cutaneous LP) or as white-gray lesions in the mouth or on the lips (oral LP). Less commonly, LP may also involve the genitals (penile or vulvar LP), scalp (lichen. Esophageal lichen planus is an underrecognized condition, with fewer than 50 cases reported to date. Unlike cutaneous lichen planus, esophageal lichen planus occurs almost exclusively in middle-aged or older women who also have oral involvement. It commonly involves the proximal esophagus and manifests as progressive dysphagia and odynophagia. Lichen planus is a recurrent, pruritic, inflammatory eruption characterized by small, discrete, polygonal, flat-topped, violaceous papules that may coalesce into rough scaly plaques, often accompanied by oral and/or genital lesions. Diagnosis is usually clinical and supported by skin biopsy. Treatment generally requires topical or intralesional.